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Cells were imaged under vehicle conditions and after stimulation with 100 nM exendin-4

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Pharmacokinetic and Pharmacodynamic Properties of Glucocorticoids as the Basis for the Optimal Selection of Antidiabetic Drugs Short-acting GS include hydrocortisone (HC) (duration of action 812 h), intermediate-acting GS are comprised of prednisolone (duration of action 1236 h) and methylprednisolone (half-life of 1840 h) which are 45 times more potent than HC, and finally long-acting GS such as dexamethasone and betamethasone are 25 times more potent than HC (duration of action 3654 h) [3,4,5,6,7,8,9,10,11,12,13,14,15,16,17,18,19,20]

Additionally, nausea is common initially and can be problematic for IBS patients with heightened gut sensitivity