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In addition to the high dosage of metformin (1,500 mg/day), a GLP-1 receptor agonist (Liraglutide, Victoza, Novo Nordisk, Denmark) was added for appetite reduction
Among patients with type 2 diabetes, discontinuation remained high at 46.5% within the first year

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After the trial period, 36% of participants on semaglutide met a composite goal of 70% timeinrange, minimal hypoglycemia and 5% weight loss, versus 0% on placebo

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