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It highlights emerging evidence, safety considerations, and equity challenges that position GLP-1 RAs as a promising public health strategy for this high-risk population.

Together, these insights serve as a comprehensive reference for the diagnosis and management of acute pancreatitis while also suggesting potential directions for future research and innovation.

Unrealised Expectations Despite progress, several anticipated 2025 milestones did not come to fruition: Regulatory progress stalled: FDAs obesity drug guidance, published in draft form in January 2025, remains unfinalised, whilst EMA has yet to update its 2016 guideline

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Liraglutide (NN2211) is a long-acting GLP-1 receptor agonist used to treat type 2 diabetes and obesity (Victoza, Saxenda)

These easy-to-use patches are designed to complement a healthy lifestyle by supporting appetite awareness, metabolism function, and overall wellness