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JAMA 2021

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Severe or progressive injection site reactions that worsen over time rather than improving, or reactions that persist beyond one week

Taken together, preclinical models of PD demonstrate the promising neuroprotective potential for GLP-1 receptor agonists to reduce inflammation and -synuclein accumulation, whilst restoring mitochondrial function and motor deficits

Some side effects (like nausea) are dose-dependent and might be milder at low doses, but others, like how it blunts appetite, could still lead to inadequate nutrient intake or a loss of lean muscle mass (called sarcopenia) if someone is losing weight without proper diet management

Presentation LBAP 022.