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9 The STEP-HFpEF DM randomised controlled trial enrolled 616 patients with obesity (BMI 30 kg/m 2 ) and both HFpEF (LVEF 40%) and T2D
We dont have much data yet and the Phase I so far was mixed, with Phase II data coming this year

Zhao L, Cheng Z, Lu Y, et al
Colonic delivery of -linolenic acid by an advanced nutrient delivery system prolongs glucagon-like peptide-1 secretion and inhibits food intake in mice

Nair KS, Halliday D, Matthews DE, Welle SL

10.1146/annurev-pathol-020117-043617 19
