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It's especially beneficial for diabetic patients who may already be at risk for peripheral neuropathy

These side effects are usually temporary and often improve as the body adjusts to the medication

High-risk (patients with a family history of ovarian cancer) patients due to genetic susceptibility to ovarian cancer should be counseled and managed according to established guidelines

Patients with certain genetic profiles may be more prone to early fatigue because their GLP-1 receptors are more responsive, or their dopamine pathways react more sharply to medication initiation

Starting at low doses and gradually increasing over weeks to months improves tolerability by allowing GI adaptation

They are prepared by 503A or 503B compounding pharmacies using semaglutide base powder formulated into a liquid suspension