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GLP-1R is expressed by various populations of central neurons, but it is still not fully clear which specific populations mediate the effects of GLP-1RAs

No need to return the product

Always follow the specific titration guidance in the product's SmPC

Substance use and psychotic disorders, seizures, neurocognitive disorders (including Alzheimers disease and dementia), coagulation disorders, cardiometabolic disorders (heart attack, heart failure, ischemic stroke, and hemorrhagic stroke, pulmonary embolism, pulmonary hypertension, coagulopathy and clotting disorders) chronic kidney disease, COPD, pneumonia, liver failure, inflammatory bowel disease, liver cancer) all significantly declined

These guidelines are not arbitrary

Clinicians should encourage safer drinking practices but recognize that patient goals vary