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Both semaglutide and tirzepatide are well-known for their effects on weight loss and blood sugar control, but our study suggests they may also offer substantial benefits to patients with obesity and type 2 diabetes by reducing adverse heart failure outcomes. Despite promising results from existing randomized controlled trials of semaglutide and tirzepatide in those with obesity-related HFpEF, regulatory authorities and professional societies have not approved or endorsed the use of these drugs for HFpEF, due in part to the studies relatively small sample sizes and unknown generalizability

Controlling weight gain by following BMI recommendations helps

This ensures higher efficacy, reduced side effects, and improved patient compliance compared to oral or injectable routes [78]

Hair loss associated with Ozempic use is not formally quantified in clinical trial data or post-marketing surveillance reports submitted to the MHRA

Of the participants, 12.2% receiving 9 mg retatrutide, 18.2% receiving 12 mg retatrutide and 4% receiving placebo discontinued treatment due to adverse events

Thats why semaglutide is often used for type 2 diabetes and medical weight loss