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While tirzepatide is a GLP-1 agonist, it also works on GIP, which may make it more effective, but studies are limited at this time

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Retatrutide Half-Life and Pharmacokinetics Retatrutide has a ~6-day half-life achieved through fatty acid albumin binding comparable to semaglutide (~7 days) and tirzepatide (~5 days)

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