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Patients should be counseled to report immediately any new or worsening visual symptoms including: Blurred or distorted central vision Difficulty reading or recognizing faces Straight lines appearing wavy (metamorphopsia) Dark or empty areas in central vision Sudden vision loss or floaters Home monitoring with an Amsler grid can help patients with AMD detect subtle changes in central vision between appointments, as recommended by the NEI and AAO

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The glucagon component adds a thermogenesis effect

Interpretation of these results must consider that the metabolic syndrome criteria have been applied to a population with a diagnosis of diabetes mellitus and on antidiabetic treatment (except SURPASS-1) and many participants received treatment for hypertension or hypercholesterolemia

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Titration and individual tolerance matter more than the drug itself
