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4 Still, this research shows what happens when you stop the medications suddenly without a gradual decrease in dose (a taper), and with adequate lifestyle support alongside it

Chronic kidney disease GLP-1 RAs have been associated with modest SBP reductions in patients with chronic kidney disease (CKD), with evidence derived largely from T2DM trials

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Elevated blood sugar causes osmotic diuresis, where excess glucose pulls water into the urine

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Tirzepatide also activates GIP receptors
