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doi: 10.1056/NEJMoa1611925 8 WiviottSDRazIBonacaMPMosenzonOKatoETCahnAet al

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Of them, chlorogenic acid is noteworthy as a lipid regulator and lipid oxidizing reduction that may be beneficial in preventing cardiovascular disease (46)

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However, the data presented here in conjunction with clinical data on this mechanism in ALS suggests that it may not be of value to perform clinical studies with GLP-1 agonists in ALS and that resources may be more usefully focussed elsewhere