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There are almost 180 million non-diabetic obese or overweight patients in the United States [2], just under half of whom seek pharmacological treatment to help with weight loss [3]
Testosterone therapy followed a similar arc: cultural hype, DTC boom, quiet fade

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Mechanisms controlling glucose-induced GLP-1 secretion in human small intestine

Cardiovascular phenotype in HFpEF patients with or without diabetes: a RELAX trial ancillary study
Retatrutide is a triple hormone receptor agonist, while Ozempic is a GLP-1 receptor agonist
