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Semaglutide for treatment of overweight and obesity: A review

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All studies were interventional, meaning they actively tested GLP-1 as a treatment intervention rather than simply observing existing conditions

Furthermore, imbalances in gut microbiota can impair the production of crucial metabolites like SCFAs, disrupting gut-brain signaling and leading to dysregulation of the hypothalamic-pituitary-adrenal (HPA) axis