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Description
GLP-1 receptor agonists bind to GLP-1 receptors on pancreatic beta cells, stimulating glucose-dependent insulin secretion while suppressing inappropriate glucagon release
In a large study of over 18,000 patients, those taking tirzepatide lost about 15.3 percent of body weight in one year compared to 8.3 percent with semaglutide

In mice, the GLP-1 receptor is expressed more in lung tissue compared to other organs, such as the small intestine, brain, heart, and kidney

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[DOI] [PubMed] [Google Scholar] 98.Qin W., Yang J., Deng C., Ruan Q., Duan K

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