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GLP-1 medications may help colon cancer patients live longer by reducing inflammation and improving metabolic health, UC San Diego researchers found in a 6,800-patient study.

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However, DPP-4 inhibitors have not reduced the risk of major adverse cardiovascular events, possibly because potentiation of SDF-1 enhances plaque growth and instability, activates deleterious neurohormonal mechanisms, and promotes cardiac inflammation and fibrosis