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Moreover, all patients on GLP-1 RAs, irrespective of drug type, dose, duration of therapy, and absence of symptoms, can have delayed gastric emptying

That makes the rise in calls to poison control centers for GLP-1 exposure unsurprising, but no less concerning, said Anthony Jaworski, clinical program manager of the Poison Control Center at Childrens Hospital of Philadelphia

This long-term persistence could therefore be because initial effects of TAM are slow to arise and/or indelible (e.g., epigenetic changes), or because they reflect effects of TAM withdrawal rather than TAM itself

It is what the paper calls "the latest tactic in an increasingly desperate scramble" to repair the firm's "threadbare finances" and avoid being nationalised

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Figure 1 - LIS Technologies Inc