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J Clin Endocrinol Metab 2007;92:1249-1255

These drugs bind to GLP-1 receptors on pancreatic beta cells, stimulating glucose-dependent insulin secretionmeaning they promote insulin release only when blood glucose levels are elevated

Spending on shareholder enrichment appears to take priority over research and development (R&D), with Novo Nordisk spending 41% more on dividends and buybacks than on R&D over the past five years

Statistical analysis Analysis was based on non-parametric tests due to low sample sizes in rare clinical outcome groups and to receive more robust information regarding outliers

studies have shown that it also has a certain protective effect on reducing the incidence of cardiovascular disease in some high-risk groups

Sometimes Trulicity is prescribed together with other diabetes drugs, including Januvia