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People with type 2 diabetes either resist the effects of insulin a hormone that regulates the movement of sugar into your cells or dont produce enough insulin to maintain normal glucose levels

J Clin Med, 12(18)

Feb 21, 2026 Your joints ache before you even get out of bed

Among those who had a measurement, the absolute change was calculated as the difference to the last value available before treatment initiation in mmol/mol for HbA1c, mL/min/1.73 m 2 for eGFR, and mmol/L for lowdensity lipoprotein (LDL) cholesterol, and triglycerides

Specifically, STAT1 is thought to play a role in transcriptional regulation as the promoter region of DPP-4 contains an interferon-gamma-activated sequence (GAS), which is an activated STAT1 binding site