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EL conceptualised the study, performed and interpreted the analyses, visualised the results, developed the methodological pipeline, searched the literature and contributed to writing the manuscript

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Then, sections were rinsed in PBS and mounted onto Superfrost Plus glass slides (Thermo Scientific, Waltham, MA USA) and coverslipped with DAPI mounting medium

For the assessment of the changes from baseline following GLP-1-based therapies in % FMD and IMT, mean differences with 95% confidence intervals (CI) were calculated between baseline samples and end-of-treatment samples for each study and then an overall effect size was generated

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