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It joins a class of new medications that are transforming obesity, a condition that affects 100 million American adults and is linked to a spectrum of diseases including diabetes, heart disease, sleep apnea, liver disease, kidney disease and joint pain

At standard therapeutic doses, tirzepatide generally produces greater weight loss than semaglutide in head-to-head comparisons

However, these benefits are short-lived, often waning within days

TTE revealed a reduced LVEF and WMA in the inferolateral walls with akinesis of the basal mid septum

Reduced mitochondrial respiratory capacity in patients with acute episodes of bipolar disorder: could bipolar disorder be a state-dependent mitochondrial disease

Chmielewski, J