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In a pooled analysis of clinical trials assessing patients with heart failure with preserved ejection fraction (HFpEF), including the STEP HFpEF and STEP HFpEF DM trials, as well as in the FLOW and SELECT trials, semaglutide improved New York Heart Association (NYHA) class IIIV symptoms, physical limitations, exercise function, associated with a 30% reduction of N-terminal pro-brain natriuretic peptide and a 31% reduction in the composite endpoint of cardiovascular death and the need for treatment intensification or hospitalization for heart failure-related events (HR 0.69
[10] [11] They should be used with caution in patients with severe gastroparesis or other severe gastrointestinal diseases
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Whatever the mechanism, most users find that reactions are localized, temporary, and inconsistent appearing for a few weeks, then disappearing without explanation
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2 Amylin wird gemeinsam mit Insulin in der Bauchspeicheldrse gebildet und frdert ein frhes Sttigungsgefhl
