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(2022) Two-year effects of semaglutide in adults with overweight or obesity: the STEP 5 trial

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No difference in weekly results

Surgical interventions may be considered for select patients with advanced disease unresponsive to conservative management

Irving P, Barrett K, Nijher M, de Lusignan S

In patients with depression, the function of the PFC and hippocampus is disrupted, whereas the amygdala is hyperactivated (Serafini, 2012)
