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Description
These drugs work by stimulating the pancreas to produce more insulin, which helps lower blood glucose levels

In the STEP 1 trial extension, people who came off semaglutide regained around two-thirds of the weight they had lost within a year (Wilding et al., 2022)

They also skip over the Zepbound maintenance dose after goal weight which is individualized

It plays a role in appetite signaling, insulin secretion, and gastric emptying

[DOI] [PMC free article] [PubMed] [Google Scholar] 41.Gullaksen S, et al

More severe side effects include pancreatitis (inflammation of the pancreas), gallbladder issues, and potential interactions with other medications
