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For patients who do not respond adequately to conventional DMARDs, advanced therapies are available through NHS specialist services

Zhang YL, Zhou C, Li XF, et al

Phase 5: Maintenance dose (week 17 onward) Dose: 2.4 mg once weekly (maximum therapeutic dose for weight management) At the maximum 2.4 mg dose, even 2.5 mg/mL is getting close to syringe capacity at 96 units

Tirzepatide uses a different titration schedule and different target doses

According to the CDC, "people who have overweight or obesity, compared to those with healthy weight, are at increased risk for many serious diseases and health conditions." Those risks include hypertension, coronary heart disease and stroke