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Description
We sought to investigate the real-world impact of sodiumglucose cotransporter 2 inhibitor (SGLT2i) and glucagon-like peptide-1 receptor agonist (GLP-1 RA) therapy in individuals with type 1 diabetes in relation to effect on blood glucose levels, adverse events and cardio-renal outcomes

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Mechanistic studies found that BA1b promoted the secretion of incretin (GIP and GLP-1) by up-regulation of VDAC1 gene expression levels

Neoepitopes were identified in DS and DP semaglutide follow-ons, indicating potential immunogenicity
