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In addition, dapagliflozin attenuated the progression of diabetic cardiomyopathy by activating AMPK, mTOR and NOD-like receptor 3 (NLRP3) inflammasome in T2DM mice [105]
The NYU Langone teams meta-analysis confirmed and broadened these findings
10.1111/jog.16009 J Obstet Gynaecol Res
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Moreover, in diabetes, mechanisms that normally counteract increased oxidative stress, such as upregulation of HO-1, are impaired, leading to loss of ICC and subsequent delay in gastric emptying
