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The GIP receptor activation in Retatrutide and Tirzepatide appears to provide some gastrointestinal protection compared to pure GLP-1 agonists like Semaglutide

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For example, it may be that the foods used to replace the red or processed meat conferred the health benefit

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Reduced gastric and intestinal motility causes slower absorption of nutrients from GI tract resulting in a gradual increase of glucose levels in general circulation