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The number of reported serious side effects was higher with liraglutide (11%) compared to semaglutide (7.9%) or placebo (7.1%)

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It is meant for overweight patients, generally with a BMI greater than 27.5

Research shows baseline metabolic markers and GLP-1 receptor genetic variants significantly affect treatment response variability across populations

The present data underscore the need for prospective, randomized clinical trials designed to systematically evaluate mood, anhedonia, and cognitive function as primary or key secondary endpoints in patients with comorbid depression and metabolic disorders