glp 1 and kidney function Renal effects of GLP-1 receptor agonists tirzepatide in individuals with type 2 diabetes: seeds of a promising future | Endocrine Kidney Outcomes With Glucagon-Like Peptide-1

Identified as the first incretin in the 1970s (see section I), GIP has historically been thought to have little therapeutic potential

10.1021/jm9909645 70 KoltermanO

observed that the improvement in the glycemic control potentiates insulin secretion induced by oral glucose ingestion but does not change the insulin secretion after iv glucose infusion indirectly demonstrating that the incretin effect is dependent of glucose/food absorption by the intestines [9]

Instead, it is designed as a consistent daily tool to help regulate hunger, improve digestion, and support gradual weight management over time

Results were similar across both cohorts in the as-treated analyses, Table 2

NOTES None Acknowledgements Fig