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One targets a single hormone pathway

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Instead, the levels of total testosterone and free testosterone were found to be indicators of congestive heart failure

Particularly noteworthy was that these EMT biomarkers were substantially reduced in rats with CKD following treatment with dulaglutide, suggesting that GLP-1 analogs may hold significant potential for patients undergoing PD, especially patients with diabetes, in extending the durability of PD and preventing PD failure

Isolated case reports and small series have described altered thyroid function tests in patients treated with GLP-1RAs, including suppressed TSH or fluctuating free thyroid hormone levels, but these changes were typically transient and not associated with progression to overt thyroid dysfunction [30,32]

T., Reynolds, J