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Some research suggests these drugs can influence macrophage polarisation, shifting immune cells towards a less inflammatory phenotype

Interestingly, in colonic mucosal biopsies from individuals with inflammatory bowel disease, these genes were upregulated in inflamed tissue compared with noninflamed mucosa from the same patients, while GLP1R expression was downregulated

Int J Mol Sci 2022;23:14631.ArticlePubMedPMC 86

Glucagon Receptor Signaling and Lipid Metabolism

Healthcare providers administer liraglutide injection using an injector pen, and patients use it along with diet and exercise to improve glycemic control in adults and pediatric patients aged 10 years and older with type 2 diabetes mellitus

However, this route is associated with several drawbacks