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12 Furthermore, GLP-1RAs reduce the secretion of proinflammatory cytokines, namely interleukin 6 (IL-6) and tumor necrosis factor alpha (TNF-), which are often elevated in neuroinflammatory conditions like migraine
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Although much research has focused on mechanisms within the central nervous system to explain this pain suppression 8 , we hypothesize that additional mechanisms occurring in the peripheral nervous system are based on hormonal regulation during digestion

Hormone support becomes metabolic balance
