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In patients receiving GLP-1 RAs for diabetes, the most obvious harm from holding them is poorly controlled blood glucose

As of now, retatrutide has not yet received FDA approval

This data lets your provider customize your escalation timeline, reducing both the temptation to self-adjust and the risk of accidental overdose

Hydration: Sometimes thirst is mistaken for hunger, especially as GLP-1s can change how your body signals dehydration

Extrapolating those results to other populations is not supported by the trials

Within this landscape, tirzepatide stands out because of its dual GIP/GLP-1 mechanism, which produces superior weight loss compared to GLP-1-only medications