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Daniel Drucker, an endocrinologist and professor at the University of Toronto, and Danish physician Dr

It commonly presents with acute focal lower quadrant abdominal pain and may mimic appendicitis, colitis, or diverticulitis

Both are taken once daily and have strong clinical evidence supporting their effectiveness for weight management

Some providers consider Ozempic and Wegovy to be breastfeeding-safe

This does not eliminate TMAO production entirely, as some circulating levocarnitine can be excreted into the gut, but it likely reduces the total TMAO burden compared to equivalent oral doses

Finally, for those with severe obesity (BMI 40 kg/m, or 35 kg/m with significant comorbidities) who have not responded to medical management, bariatric surgery remains a highly effective option and should be discussed with a specialist