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Description
10.1056/NEJMoa2108269 28 GilbertM
What sets GLP-1 receptor agonists apart is their broad impact
PMID 19810843
Leptin suppresses the orexigenic effects of NPY while promoting the anorexigenic pathway via POMC/CART activation, decreasing food intake and promoting weight loss
Conclusions According to this multidisciplinary consensus, GLP-1 RAs can be considered easy-to-manage, highly effective medications with a good profile of tolerability to treat people with obesity or T2D
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