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We have previously examined GLP-1 RA switching between January 2018 and October 2023, finding that switching patterns varied across medications and time but often reflected the impact of drug supply shortages

Chen Li contributed to methodology and data curation

Funding Open access funding provided by The Science, Technology & Innovation Funding Authority (STDF) in cooperation with The Egyptian Knowledge Bank (EKB)

[DOI] [PMC free article] [PubMed] [Google Scholar] 820.Quarta C., Clemmensen C., Zhu Z., Yang B., Joseph S.S., Lutter D

In contrast to older stepwise models, todays diabetes treatment approach using GLP-1 therapies is far more flexible and individualized

Scroll to view more GLP-1R activation in the pancreas enhances the secretion of insulin when elevated levels of blood glucose are present, and when coupled with GIPR activation in the pancreas, which stimulates beta cells to ramp up insulin production, blood sugar can be more effectively regulated in the treatment of Type 2 diabetes