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GLP-1 induces barrier protective expression in Brunners glands and regulates colonic inflammation

Liraglutide (Saxenda) Liraglutide works through the same GLP-1 pathway but has a different dosing schedule than other options on the market, requiring a daily rather than weekly injection

Symptoms can come on suddenly and include severe abdominal pain, nausea, vomiting, or fever

Leptin signaling in the medial nucleus tractus solitarius reduces food seeking and willingness to work for food