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Incretins are estimated to account for approximately 5070% of the total insulin secretion after oral glucose administration, and this has been dubbed the incretin effect

These effects often diminish as patients adjust to medication

However, the choice between these weight loss medication options should be made in consultation with a healthcare provider, considering all factors, including medical history, side effects, and cost

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Acknowledgements This research was supported by the Fundao de Amparo Pesquisa do Estado de Minas Gerais (FAPEMIG) (Grant Number: APQ 01453-15 and PPM 00282-11)

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