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Summary The use of GLP-2 analogs is effective in the management of SBS-IF and may show promise in the treatment of other severe gastrointestinal disorders associated with loss of effective intestinal resorptive surface area.

Risk of bias was assessed using an adapted Quality Assessment Tool for In Vitro Studies (QUIN) tool

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In peptide research studies, Semaglutide is frequently examined for its interactions with GLP-1 receptor pathways, making it a compound of interest in laboratory research focused on metabolic regulation, endocrine signaling, and cellular response mechanisms