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Simon TG, Roelstraete B, Hagstrm H, Sundstrm J, Ludvigsson JF

While creatine is generally well-tolerated, some patients may experience mild digestive upset when starting, which usually resolves with continued use

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There are currently three approved DPP-4-resistant GLP-1RA therapies: exenatide, a GLP-1-like xenopeptide and two GLP-1RAs liraglutide, a human GLP-1 analogue, and the recently approved exendin-4-based agent lixisenatide

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TIX100 is already FDA IND-cleared in diabetes and has demonstrated Phase 1 safety in healthy volunteers
