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Hence, in 2022, glucose-lowering efficacy and proven cardiovascular effects were important for the strong positioning of semaglutide, dulaglutide and tirzepatide in guidelines on the management of hyperglycaemia in type 2 diabetes [33], and a similar strong positioning of incretin therapy was seen in guidelines on primary care [39]

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PD actually involves dysfunction in dopamine metabolism in many parts and regions of the brain, including synthesis, secretion, transport, reuptake, elimination, and receptor binding of DA (16)