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It is still unclear whether these genetic variants influence weight loss outcomes from GLP-1 drugs such as Ozempic and Wegovy, which are increasingly used to treat obesity

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26 The drug that has advanced furthest through development, in fact all the way to market, is Eli Lilly and Companys (Indianapolis, Indiana, USA) tirzepatide (LY3298176), a unimolecular dual GIP/GLP-1 RA

This is especially important if you have a history of GI surgery, diabetes complications, or are taking other medications affecting digestion

By mimicking GLP-1, semaglutide powerfully promotes weight loss: it reduces hunger, increases feelings of fullness (satiety), and regulates blood sugar

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