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In this episode, we explore the use of GLP-1 therapy for weight management beyond diabetes, including who may benefit and who should avoid it.

However, the role of GLP-1R in the pathological process of OA is unclear

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Methods We investigated the metabolic and mechanistic effects of combining semaglutide (GLP-1RA) with Akkermansia muciniphila 11 (Akk11) in db/db mice, a model of T2D-associated MASLD

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