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You may be a fit if you have a BMI of 27+ (or 25+ with a weight-related condition), have struggled to lose weight through diet and exercise alone, want a clinically-studied medication with provider supervision, or want a clinically-studied, long-established GLP-1 medication

Similarly, although patients treated with exenatide or liraglutide may experience injection-site reactions and, rarely, localised transient urticaria, the skin has not traditionally been viewed as a site of incretin action

Obestatin promotes survival of pancreatic beta-cells and human islets and induces expression of genes involved in the regulation of beta-cell mass and function.Diabetes

We mention them only so you can recognise the terms in factual coverage

See also Supplemental Figures 1 and 6

But its important to be clear that these medications alone are not a cure for chronic obesity, nor does every individual respond to them in the same way