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Over 18 months, the condition occurred in approximately 8 cases per 10,000 GLP-1 users, compared with 4 to 6 cases among comparison groups

According to William Hinojosa, DO, a general surgeon with Oklahoma Surgical Associates, the benefits of GLP-1 medications are significant, but its important for patients to understand potential side effects

The results of the PIONEER-3 trial have now been published in the renowned journal Journal of the American Medical Association (JAMA) and are said to be trend-setting for future therapy of type 2 diabetes.

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The interaction between the upper gastrointestinal tract and the endocrine system is important in the regulation of metabolism and of weight (Figure1)

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