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Young: Exactly

& Sager, P

The real question isnt just whether they deliver results

Mechanically, insulin mainly activates two signal pathways: insulin receptor (IR)-insulin receptor substrates (IRS)-phosphatidylinositol 3-kinase (PI3K)-protein kinase B (AKT) signal pathway (Pollak, 2008)

So far, no strong data suggests that people with psychiatric conditions respond differently to GLP-1s, says Samantha Catanzano, PharmD, a psychiatric pharmacist at UT Health Austins Bipolar Disorder Center in Texas

5 GI events like nausea, diarrhea, constipation, vomiting, and dyspepsia were the most frequently reported adverse effects