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The first three months after starting or escalating retatrutide are the most likely period for disruption

Research suggests that Ozempic-related diarrhea can be effectively managed with appropriate treatment strategies

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doi: 10.1016/S0140-6736(21)01501-4 32 CandrilliSDDavisKLKanHJLuceroMARousculpMD

The Rome IV criteria recommend a stepwise approach: initial treatment with a bulk-forming agent, followed by an osmotic laxative and then a stimulant laxative if needed