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Additionally, the "lowers A1C" claim rests on a result that didn't reach statistical significance
Gastrointestinal effects and referred pain: The pronounced gastrointestinal side effects of GLP-1 therapyparticularly nausea, constipation, and abdominal distensioncan occasionally manifest as referred pain to the back

1,5 Injections are administered weekly, whereas tablets are taken daily

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Lixisenatide In the ELIXA (Evaluation of Lixisenatide in Acute Coronary Syndrome) study, T2D patients with a recent coronary artery event were randomly assigned (1:1) to a lixisenatide (1020 g) group or placebo group (Pfeffer et al., 2015)