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The IRRs of pancreatic cancer (0.74), thyroid cancer (1.32), and medullary thyroid cancer (0.34) did not significantly increase in the GLP-1 RA group compared with those in the DM control group
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Beyond that, some other potential risks included sleep issues, low blood pressure (sometimes leading to fainting), kidney stones, arthritis, and acute pancreatitis
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Just a few years later, in 2021, the FDA approved semaglutide at a 2.4 mg dose specifically for chronic weight management in adults with obesity or overweight conditions
